Home Health Lung Cancer Screening Dramatically Increases Long-term Survival Rate

Lung Cancer Screening Dramatically Increases Long-term Survival Rate

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Chicago, November 22, 2022 /PRNewswire/ — Diagnosing early lung cancer with low-dose CT screening significantly improves long-term survival for cancer patients, according to a large 20-year international study to be published next week. annual meeting Radiological Society North America (RSNA).

“Screening does not prevent cancer from occurring, but it is an important tool in identifying early-stage lung cancer that can be surgically removed,” said the study’s first author. Claudia HenschkePh.D., MD, Professor of Radiology and Director of the Early Pulmonary and Cardiac Activity Program at Icahn School of Medicine, Mount Sinai New York.

Lung cancer is the leading cause of cancer death. According to the American Lung Association, the average five-year survival rate for lung cancer is 18.6%. Only 16% of lung cancers are diagnosed at an early stage, and more than half of lung cancer patients die within a year of their diagnosis.

Treatment of more advanced stages of cancer with targeted therapies and immunotherapies has come a long way, but the best tool to combat cancer deaths remains early diagnosis with low-dose CT screening, before symptoms appear. is to do

“Symptoms occur primarily in late-stage lung cancer,” Dr. Henschke said. “So the best way to detect early-stage lung cancer is to enroll in an annual screening program.”

Dr. Henschke and colleagues have spent years studying the efficacy of low-dose CT screening for cancer detection. The investigator’s efforts to advance his CT screening for early lung disease led to the creation of the International Early Lung Cancer Action Plan (I-ELCAP). Launched in 1992, this multi-institutional, multinational research program has enrolled over 87,000 participants from over 80 institutions.

In 2006, researchers found that patients whose cancer was identified by CT screening had an 80% 10-year survival rate. This study examined 20-year survival rates.

“What we present here is a 20-year follow-up study of screening program participants who were diagnosed with lung cancer and subsequently treated,” said Dr. Henschke. “The key finding is that even after this long period of time, no one has died from lung cancer.”

The study found a 20-year survival rate of 80% among 1,285 I-ELCAP participants diagnosed with early-stage lung cancer. Survival was 100% for both 139 participants with non-solid carcinoma pulmonary nodules and 155 participants with partially solid nodules. The 991 participants with solid nodules had a survival rate of 73%.

The investigators also estimated survival rates for clinical stage IA lung cancers with a mean diameter of 10 mm or less in length and width on the same CT image and for resected pathological stage IA lung cancers. Stage I lung cancer is a very small tumor that has not spread to any lymph nodes.

Despite consistency, stage IA clinical participants had an 86% lung cancer survival rate. Pathologically he had a 92% 20-year survival rate for patients with stage IA cancer ≤10 mm.

Results show that after 20 years, patients diagnosed with early lung cancer by CT screening have significantly better outcomes. By surgically removing the cancer when it is small enough, the patient can be cured effectively in the long term.

The findings demonstrate the importance of regular and early screening.

“Ultimately, anyone interested in getting screened should know that even if they are unlucky enough to develop lung cancer, it can be cured if caught early,” Dr. Henschke said.

The U.S. Preventive Services Task Force recommends annual lung cancer screening with low-dose CT in adults aged 50 to 80 who have smoked for 20 pack years and who are current smokers or have quit within the past 15 years. Recommended.

co-author is David F. JankelevitzMD, Daniel M. Libby, james smithMD, Mark PassmentierMD, and Rowena YipMPH

Note: Copies of the RSNA 2022 news release and electronic images are available online. RSNA.org/press22.

RSNA is an association of radiologists, radiation oncologists, medical physicists, and related scientists that advances excellence in patient care and healthcare delivery through education, research, and innovation. .The association is based on Oak Brook, Illinois.RSNA.org)

For patient information about lung cancer screening, visit RadiologyInfo.org.

SOURCE Radiological Society North America (RSNA)

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