New research offers hope for the future in the fight against Parkinson’s disease and opens the door to new ways to deliver treatment to patients suffering from a devastating neurodegenerative disease.
was announced in movement disordersThis study highlights how experts were able to cross the blood-brain barrier using magnetic resonance guided focused ultrasound (MRgFUS) through microbubbles. In doing so, researchers were able to target treatments to a specific region of the brain, the putamen.
The blood-brain barrier protects the brain from toxins, but it also makes it harder for therapeutic drugs to reach their intended destinations, rendering them ineffective. , allowing clinicians to temporarily provide treatment.
This latest study is not the first example of focused ultrasound being harnessed to break through the blood-brain barrier. However, this is the first time its efficacy has been tested in treating Parkinson’s disease.
“Our early findings are an exciting and important first step in the minimally invasive direct brain delivery of therapeutics to key regions of the brain critical to the development and progression of Parkinson’s disease.” Nil Lipsman, M.D.Co-Principal Investigator and Director of Research Sunnybrook’s Harquayle Center for Neuromodulation, said in a statement.