overview: Loneliness and lack of social support increase the risk of developing Alzheimer’s and other dementias. The findings support growing evidence linking social isolation and Alzheimer’s disease.
sauce: PLOS
Social lifestyle determinants, including social isolation, are associated with neurodegenerative risk factors, according to a new study published this week in an open-access journal. pro swan By Kimia Shafigui and colleagues at McGill University, Canada.
Alzheimer’s disease and related dementias (ADRD) is a growing public health crisis with an annual global cost of over $1 trillion. Although there is increasing evidence that social isolation is associated with an increased risk of ADRD, the association between social lifestyle and other known ADRD risk factors for him is less well understood.
In the new study, researchers studied data from 502,506 UK Biobank participants and 30,097 Canadian Longitudinal Studies on Aging enrolled in the study. Both studies had questionnaires that included questions about loneliness, frequency of social interaction, and social support.
This study found numerous associations between potentially modifiable ADRD risk factors and both loneliness and lack of social support. An individual who smoked heavily, drank excessive alcohol, experienced sleep disturbances, and frequently failed to participate in mild to vigorous physical activity (all known risk factors for his ADRD) was likely to be lonely and socially inept. It became more likely that there was a lack of support.
For example, CLSA found that more regular physical activity with others was associated with a 20.1% lower probability of feeling lonely and a 26.9% lower probability of having insufficient social support.
Physical and mental health factors previously associated with ADRD, including cardiovascular disease, visual or hearing impairment, diabetes, neurotic and depressive behaviors, are also associated with both subjective and objective social isolation. was related. For example, in UKBB, hearing difficulties due to ambient noise increased the likelihood of feeling lonely by 29.0% and the likelihood of lacking social support by 9.86%.
As a function of participants’ neurotic scores, they were also 3.7 and 1.4 times more likely to feel lonely and lack social support, respectively.
The authors conclude that social isolation, which is more easily modifiable than genetic or latent health risk factors, may be a promising target for preventive clinical behavior and policy intervention.
The authors concluded, “Given the uncertainty of the impact of social distancing measures imposed by COVID-19, our findings suggest that social isolation multiple It underscores the importance of investigating scale effects,” he adds.
About this Alzheimer’s Disease Research News
author: press office
sauce: PLOS
contact: Press Office – PLOS
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Original research: open access.
“Social isolation is associated with the classic risk factors for dementia associated with Alzheimer’s diseaseby Kimia Shafigui et al. pro swan
overview
See also
Social isolation is associated with the classic risk factors for dementia associated with Alzheimer’s disease
Alzheimer’s disease and its associated dementias are a major public health burden and will become more serious in the coming years due to longevity. Recently, there has been clinical evidence implicating the experience of social isolation in accelerating the onset of dementia.
In 502,506 UK Biobank participants and 30,097 participants from the Canadian Longitudinal Study of Aging, we examined traditional risk factors for developing dementia in the context of loneliness and lack of social support. I reconsidered.
Across these measures of subjective and objective social deprivation, we identified strong associations between an individual’s social capital and various indicators of Alzheimer’s disease and related dementia risk. This was replicated in both population cohorts.
The quality and quantity of everyday social encounters are the major etiological and pathological factors representing 1) individual habits and lifestyle factors, 2) physical health, 3) mental health, and 4) social and external factors. It had a lot to do with factors.
Our population-size assessment suggests that social lifestyle determinants are associated with most neurodegenerative risk factors, highlighting them as promising targets for preventive clinical action. increase.
