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People who belong to blood group Rh(D) have elevated risk of parvovirus infection

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According to a study published in , the risk of contracting parvovirus is higher in people with blood type Rh (D). infectious disease journal Developed by researchers at the Karolinska Institutet in Sweden in collaboration with Octapharma.

The fifth disease is a viral disease caused by parvovirus. Most often, school-aged children are affected by common symptoms such as red patches on their cheeks, which can spread to their arms and legs. .

In a new study, researchers can now demonstrate that a person has an increased risk of getting the disease if they belong to what is called rhesus monkey D antigen, or Rh(D). and the Rh series are the most common.

All infected belonged to Rh(D)

In Germany, more than 160,000 blood donors were screened for parvovirus between 2015 and 2018. Of the blood donors, 22 had the virus. All infected persons belonged to blood group Rh(D).

This is an important, yet unreported, finding that Rh(D) is important for virus entry into host cells, and may be novel because the virus’ cellular receptor has not yet been identified. . ”

Rasmus Gustafsson, Affiliated Research Fellow, Department of Clinical Neuroscience, Karolinska Institutet, Project Manager, Octapharma

there was a high proportion of women

Researchers were also able to confirm that the risk of infection increases during the summer months. In addition, not only women but also those from her 31 to her 40 are at increased risk of infection.

“At that age, you usually have young children around you. We already know that young children get infected before they start school and then infect their parents afterwards. It could be a reflection of the fact that there is a need to enter a care profession and take care of children,” says Rasmus Gustafsson.

This study was conducted in collaboration with Octapharma, with which some of the co-authors are active.


Journal reference:

Healy, K. and others. (2022) Prevalence of parvovirus B19 viremia in German blood donations and its relationship with ABO and rhesus blood group antigens. Journal of Infectious Diseases. doi.org/10.1093/infdis/jiac456.

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