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Some comorbidities raise death risk from COVID-19

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Previous studies have found associations between comorbidities or pre-existing conditions and an increased risk of death in COVID-19 patients. But new research from the Department of Veterans Affairs suggests that certain types of pre-existing conditions may put COVID patients at higher risk of death than others.

in the Largest study ever To follow COVID-19 patients to predict mortality, New Mexico VA researchers studied COVID outcomes in 347,220 COVID patients treated at VA facilities as of September 2021. Did. Through research, they developed a new predictive model, PHDeathDX, to predict deaths from COVID-19.

“Models using traditional comorbidity indices often assign little weight or typically do not include the highest-risk conditions, thus pre-existing conditions to model COVID-19 mortality. “It shows a clear advantage of using an unrestricted set. The same holds true for conditions associated with the severity of COVID-19,” the authors wrote. We suggest that selecting comorbidities for analysis without systematically reviewing all comorbidities experienced by patients is risky.”

Researchers evaluated COVID-19 patients with various pre-existing medical conditions to assess which patients were most likely to die from COVID.they found high blood pressure Also, certain types of neurodegenerative diseases, such as Alzheimer’s disease and dementia, are among the pre-existing conditions that increase mortality risk in COVID patients.

“Hypertension was the most important independent risk factor for death and was a greater threat than coronary artery disease,” the authors wrote. , malignant tumors accounted for the majority of the high-risk conditions.”

This study was published in an online journal Biological methods and protocols.

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