Excess weight in adulthood leads to health complications such as diabetes, hypertension, and dyslipidemia. Obesity is increasingly recognized as a multisystem disease affecting the respiratory, gastrointestinal, and cardiovascular systems.
Previous studies have demonstrated links between obesity and AD-related changes such as amyloid accumulation and cerebrovascular disease. However, no studies have yet directly compared patterns of brain atrophy between Alzheimer’s disease and Alzheimer’s disease. obesity.
According to a new study by scientists at The Neuro (Montreal Neurological Institute-Hospital), McGill University Neurodegeneration and Alzheimer’s disease (AD) patient.
Scientists have investigated the following patterns gray matter shrinkage Obesity and Alzheimer’s disease studies using a sample of over 1,300 people. They created maps of gray matter atrophy in each group and compared Alzheimer’s patients with healthy controls, obese and non-obese individuals.
Scientists have found similar effects of obesity and Alzheimer’s disease on gray cortical thinning.For example, both groups showed similar levels of thinning hair on the left prefrontal cortex and the right temporoparietal cortex. Neurodegeneration may be indicated by cortical thinning. This means that obesity can cause the same kind of neurodegeneration as AD patients.
Dr. Philip Morris, a researcher at The Neuro and the first author of the study, said: “Our study strengthens previous literature pointing to obesity as a key factor in AD by showing that cortical thinning may be one of the potential risk mechanisms. Our results suggest that, in addition to other health benefits, losing weight in middle-aged obese and overweight individuals may also reduce subsequent risk. neurodegeneration and dementia”
Posted in Alzheimer’s Journal Jan 31, 2022 The study also helps reveal neurological effects, showing that obesity may play a role in the development of Alzheimer’s disease and dementia.